Phenethylamines are stimulant, entactogenic, and hallucinogenic substances that share similar chemical structures with amphetamine, catecholamines, synthetic cathinones, and other substances.
Phenethylamines include both natural and synthetic substances classified into (1) classical phenethylamines like MDMA, MDEA, and MBDB; (2) psychoactive phenethylamines that include mescaline-derived compounds like TMA, DOM, DOET, DOI, and DOC; and (3) more recent compounds including bromodragonfly, benzofuran, N-benzyl substituted phenethylamines substances, and the “2C-series” (e.g., 2C-I, 2C-E, and 2C-B).
May 2024 – Alert from the NDEWS Web Monitoring Team: Reddit online mentions of 2C-E
What is 2C-E? 2C-E, also known as “Eternity”, is a Schedule I synthetic psychedelic drug in the phenethylamine class. It produces intense visual hallucinations and a heavy, introspective mental state.
What was found? Analysis of online discussions indicates a rise in interest and use of 2C-E, with activity increasing by over 400% since late 2022. A particular spike has occurred just in the past month since mid-March 2024. Discussion of 2C-E fluctuates quite wildly over time.
How is it being discussed? 2C-E has an online reputation as an intense and long-lasting psychedelic. Reddit users frequently mention strong visual effects, a heavy and sometimes dark mental space, and an uncomfortable “body load” involving nausea, vomiting, and muscle tension. Many Reddit users also mention vasoconstriction as an effect of 2C-E. The long 7-8 hour duration has earned it the nickname in online communities of “Eternity”. Discussions often warn of 2C-E’s very steep dose-response curve, where even slight dosage changes can dramatically intensify effects. Some mention combining 2C-E with MDMA or other psychedelics.