The National Precursor Log Exchange (NPLEx) is a real-time electronic logging and compliance system that tracks sales of over-the-counter (OTC) cold and allergy medications containing pseudoephedrine (PSE), precursors to the illegal drug, methamphetamine.
NPLEx is available at no cost, when states pass electronic tracking legislation, to state agencies and its users, including pharmacies, retailers, and law enforcement.
NPLEx was developed by Appriss Health to comply with the federal Combat Methamphetamine Epidemic Act enacted in 2006. Since then, NPLEx has been utilized by 33 states to comply with methamphetamine precursor legislation, as well as New York and California, voluntarily.
The program is operated by the National Association of Drug Diversion Investigators (NADDI), funded by manufacturers of pseudoephedrine medicine, and technology provided through contract by Apriss Inc.