4-AcO-DMT (or psilacetin) is a semi-synthetic tryptamine closely related to the psychedelic mushroom molecules psilocin and psilocybin.
In fact, 4-AcO-DMT is widely known as “synthetic mushrooms.” Like psilocybin, it appears that the body metabolizes 4-AcO-DMT into psilocin.
Most illicit purchaces buy psilacetin as a brown or off-white powder that can be mixed with water just prior to dosing. But it’s also available in pills, tablets, capsules, and gel tabs among other preparations.
4-AcO-DMT is federally unscheduled in the US; manufacturing, distributing, or possessing the compound for human consumption violates the Federal Analogue Act.
NDEWS Online Mentions Report (April 7, 2023)
What was found? Over the past three years, 4-AcO-DMT has shown increased activity in online drug-related subreddit discussions. The rate of total mentions saw a significant spike in late 2022.
What is 4-AcO-DMT? 4-AcO-DMT is a semi-synthetic psychoactive drug of the tryptamine class. Some researchers believe it is a prodrug for psilocin. The drug is easy to synthesize compared to other psilocybin analogs.
How is 4-AcO-DMT being discussed? Discussions of 4-AcO-DMT primarily center around the experience of the drug being like psilocybin or DMT without some negative side effects. Commenters report that the drug is cheap and easy to synthesize compared to other psychedelics.
Drug Terms: Psilacetin, O-acetylpsilocin, Synthetic Shrooms, 4-acetoxy-DMT